Ibuprofen May Up Heart Attack Risk
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Thread: Ibuprofen May Up Heart Attack Risk

  1. #1

    Default Ibuprofen May Up Heart Attack Risk

    June 9, 2005 -- Ibuprofen, naproxen, and similar pain relievers raise a person's risk of heart attack, a new study suggests.

    Ibuprofen and naproxen - traditional anti-inflammatory pain relievers -- have been considered more heart friendly than the new Cox-2 type of pain drugs. Two of the Cox-2 drugs, Vioxx and Bextra, have been pulled from the marketVioxx and Bextra, have been pulled from the market because they increase a person's risk of heart attack.

    The new study, led by Julia Hippisley-Cox, MD, MRCP, of the University of Nottingham, England, did show that Vioxx increased the risk of heart attack by 32% when taken in the previous three months. But it also linked ibuprofen -- brand names include Advil and Motrin -- to a 24% higher risk of heart attack compared with people who had not taken any anti-inflammatory in the last three years.

    Diclofenac (brand names including Arthrotec, Cataflam, and Voltaren) increased heart attack risk by 55%. Naproxen (brand names include Aleve) was also linked to a higher heart attack risk, although the finding was not as strong.

    Previous research has shown no link between occasional use of painkillers and heart attacks. Patients taking over-the-counter anti-inflammatory painkillers should not take them for more than 10 days without checking with their doctor.

    A second study by Canadian arthritis specialist Marie Hudson, MD, MPH, found that among elderly patients who already had heart disease, Celebrex -- a Cox-2 drug still on the market -- was safer than Vioxx and possibly even traditional anti-inflammatory drugs.

    Both studies appear in the June 11 issue of the British Medical Journal.

    Heart Attacks and Pain Pills

    Hippisley-Cox and colleague Carol Coupland analyzed data collected from general practices across England, Wales, and Scotland. They analyzed data from 9,218 people with first-time heart attacks and compared them to 86,349 matched patients without heart attacks.

    Those with heart attacks were much more likely to have used anti-inflammatory painkillers regularly, also known as nonsteroidal anti-inflammatory drugs (NSAIDs).

    "The list of traditional NSAIDs seems to be comparable to the Cox-2 drugs in increasing heart attack risk," says Hippisley-Cox, "but when you put that into perspective, the vast majority of people taking these drugs will not be harmed by them."

    Older patients are at the highest risk of heart attack and thus more vulnerable to the increased heart risk from pain drugs. Hippisley-Cox calculates that Vioxx would cause one extra heart attack for every 700 patients aged 65 and older taking the drug. Ibuprofen would cause one extra heart attack for every 1,000 patients taking the drug.

  2. #2
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    FIRST TIME HEART ATTACK VANDHA ENNA AaGUM

    cure panna mudiyummaa

  3. #3

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    Good information ...Thanks Teena

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    Very Good Information Teena !!!

    Thanks a lot .... I know people who take ibuprofen regularly... now thats scary news for them

    Shy
    I Geetham

  5. #5

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    thanks for the info teena,very useful....

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    thanks for the info Doc
    azhagu kutty chellam unnai aLLi thookum pOdhu, un pinju viralgaL mOdhi naan nenjam udaindhu pOnaen

  7. #7

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    thanks for the information teena....


    Lakshmi

  8. #8

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    Yikes.....really Cheers for the info Dr T

    Altogether tablets and all are no good....when I have a headache I just wash my face in ice cold water and relax for abt 5-10 mins....and that's it...best cure ever!

  9. #9

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    Well i read a sunday magazine yesterday...
    Do pills kill people indirectly............

    Most of the allopathy medicines have side affects...Medicines that are pulled off the market tend to come soon with minor alterations in the composition and with a new name..........

    Similar to the terrorist camps in pakistan...where mushraff claims the camps were abolished...but the attacks still continu.................
    I am back.........

  10. #10
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    what an analogy Vampy anna ...only you can
    Cum recte vivis, ne cures verba malorum


  11. #11
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    correcta sona sweetlotus katteri unga naala matum thaan mudiyum

    Shy
    I Geetham

  12. #12

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    General Outlook of Ibuprofen

    Ibuprofen is widely used for the relief of headache including migraine. It is also widely marketed as an analgesic agent (rather than as an anti-inflammatory) and is often used for general pain conditions including those that arise from various injuries (such as sporting injuries), illnesses (such as influenza, shingles, gout), and post-operative pain. In Europe also Ibuprofenlysinat (a salt of Ibuprofen) is licensed for treatment of the same conditions as Ibuprufen. Ibuprofenlysinat is said to have a more rapid onset of action compared to standard Ibuprofen.

    As with other NSAIDs, ibuprofen inhibits platelet aggregation, but is not used therapeutically for this action since it is a minor and reversible effect.

    It has also some Clinical Indications and it includes

    rheumatoid arthritis
    osteoarthritis
    juvenile rheumatoid arthritis
    primary dysmenorrhoea
    fever
    relief of acute and/or chronic pain states in which there is an inflammatory component

    what can u say abt this DR.Teena
    Friends give ur info to the neww pattimandram topic.thank u

  13. #13

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    thanks for the info

  14. #14
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    Though it is old topic,

    Since i am doing some research in this NASID, I would like to share my views.

    Though, NASID is a good pain reliever, consumption of NASID for 5 to 6 months will defiantly cause renal failure. So please avoid those NASID ( brufen,Naproxen, all diclofinac compounds etc.,) drugs. It severely causes renal failure.

    I have seen many cases during my research and when we tested these compounds in rats we found the same.

    So please avoid those NASID drugs.

    paul

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